এমিজাইড

Amiloride is a weak diuretic which acts mainly on the distal renal tubules. It increases the excretion of Na and reduces the excretion of K. It diminishes kaliuretic effects of other diuretics, and may produce an additional natriuretic effect.

Hydrochlorothiazide inhibits the reabsorption of Na in the distal tubules causing increased excretion of Na and water including K and hydrogen ions.

ব্যবহার

Treatment of hypertension or congestive heart failure in patients who develop hypokalemia when thiazide or other kaliuretic diuretics are used alone, or in patients in whom maintenance of normal serum potassium levels is clinically important (eg, digitalized patients); alone or as adjunctive treatment with other antihypertensive agents.

এমিজাইড এর দাম কত? এমিজাইড এর দাম

Amizide in bangla
বাণিজ্যিক নাম	এমিজাইড
জেনেরিক	Hydrochlorothiazide + Amiloride
ধরণ	ট্যাবলেট
পরিমাপ	50mg+5mg
দাম
চিকিৎসাগত শ্রেণি	Thiazide diuretics & related drugs
উৎপাদনকারী	Sanofi Bangladesh LTD,
উপলভ্য দেশ	Bangladesh
সর্বশেষ সম্পাদনা	January 7, 2025 at 1:49 am

খাওয়ার নিয়ম / ব্যবহারের নিয়ম

এমিজাইড খাওয়ার নিয়ম / ব্যবহারের নিয়ম

Adult: 1-2 tablets (5 mg amiloride & 50 mg hydrochlorothiazide) daily in single or divided doses, increasing if necessary to maximum 4 tablets.

Children: Safety and efficacy not established.

পার্শ্বপ্রতিক্রিয়া

Cardiovascular: Arrhythmia, tachycardia, palpitations (amiloride).
CNS: Headache, fatigue, tiredness, weakness, dizziness, encephalopathy, tremors, decreased libido (amiloride); restlessness (hydrochlorothiazide).
Dermatologic: Mild skin rash, pruritus, alopecia (amiloride); urticaria, purpura (hydrochlorothiazide).
EENT (eye, ear, nose, and throat): Increased ocular pressure, tinnitus (amiloride); transient blurred vision, xanthopsia (hydrochlorothiazide).
GI: Nausea, anorexia, GI and abdominal pain, flatulence, activation of peptic ulcer, dyspepsia, heartburn, dry mouth (amiloride); pancreatitis, cramping, GI irritation, sialadenitis (hydrochlorothiazide).
Genitourinary: Bladder spasm, polyuria, urinary frequency (amiloride); interstitial nephritis (hydrochlorothiazide).
Hematologic: Aplastic anemia, neutropenia (amiloride); agranulocytosis, leukopenia, hemolytic anemia, thrombocytopenia (hydrochlorothiazide).
Hepatic: Jaundice.
Metabolic: Hyperkalemia, hyperglycemia, glucosuria, hyperuricemia (hydrochlorothiazide).
Respiratory: Shortness of breath, cough (amiloride); respiratory distress, including pneumonitis and pulmonary edema (hydrochlorothiazide).

সতর্কতা

মিথস্ক্রিয়া

Amiloride ACE inhibitors (eg, captopril): May result in severely elevated potassium levels.
Potassium preparations: May severely increase serum potassium levels, possibly resulting in cardiac arrhythmias or cardiac arrest. Do not coadminister.
Hydrochlorothiazide Bile acid sequestrants: May reduce thiazide absorption; give thiazide at least 2 h before sequestrant.
Diazoxide: May cause hyperglycemia.
Digitalis glycosides: Diuretic-induced hypokalemia and hypomagnesemia may lead to digitalis-induced arrhythmias.
Lithium: Renal excretion of lithium may be reduced.
Loop diuretics (eg, furosemide): Synergistic effects may occur, resulting in profound diuresis and serious electrolyte abnormalities.
Sulfonylureas (eg, chlorpropamide): Hypoglycemic effect of sulfonylurea may be decreased, necessitating an increase in sulfonylurea dosage.

গর্ভাবস্থাকালীন ব্যবহার

Pregnancy Category B

Lactation:

Amiloride: undetermined
hydrochlorothiazide: excreted in breast milk.

বৈপরীত্য

Hyperkalemia (serum potassium levels greater than 5.5 mEq/L); concurrently with other potassium-sparing diuretics (eg, spironolactone), potassium supplements (including potassium-rich diet) except in severe or refractory cases of hypokalemia; impaired renal function; sensitivity to any components of product.