Uridine
N4-Hydroxyctidine, or EIDD-1931, is a ribonucleoside analog which induces mutations in RNA virions. N4-hydroxycytidine was first described in the literature in 1980 as a potent mutagen of bacteria and phage. It has shown antiviral activity against Venezuelan equine encephalitis virus, and the human coronavirus HCoV-NL63 in vitro. N4-hydroxycytodine has been shown to inhibit SARS-CoV-2 as well as other human and bat coronaviruses in mice and human airway epithelial cells. It is orally bioavailable in mice and distributes into tissue before becoming the active 5’-triphosphate form, which is incorporated into the genome of new virions, resulting in the accumulation of inactivating mutations. In non-human primates, N4-hydroxycytidine was poorly orally bioavailable. A remdesivir resistant mutant mouse hepatitis virus has also been shown to have increased sensitivity to N4-hydroxycytidine. The prodrug of N4-hydroxycytidine, EIDD-2801, is also being investigated for its broad spectrum activity against the coronavirus family of viruses.
ব্যবহার
Uridine is a cytidine analog being investigated to treat COVID-19.
N4-hydroxycytidine and its prodrug EIDD-2801 is being studied for its activity against a number of viral infections including influenza, MERS-CoV, and SARS-CoV-2.
Uridine এর দাম কত? Uridine এর দাম
সুচিপত্র
বাণিজ্যিক নাম | Uridine |
জেনেরিক | N4-Hydroxycytidine |
ধরণ | |
পরিমাপ | |
দাম | |
চিকিৎসাগত শ্রেণি | |
উৎপাদনকারী | |
উপলভ্য দেশ | |
সর্বশেষ সম্পাদনা | September 19, 2023 at 7:00 am |
খাওয়ার নিয়ম / ব্যবহারের নিয়ম
Uridine খাওয়ার নিয়ম / ব্যবহারের নিয়ম